Who’s the only player who’s run for over 200 yards in a game played on Thanksgiving?
O.J. Simpson. In November, 1976, Simpson ran for a single-game record 273 yards and 2 TDs in a Thanksgiving Day game at Detroit. The Bills, remarkably, lost that game 27-14. In league history, 30 other running backs have run for at least 230 yards in a game, and they all won. Buffalo returns to action on Thanksgiving this year.