Question

What player broke the NFL’s single-game rushing record in a game played on Thanksgiving?

Answer

O.J. Simpson. In 1976, Simpson ran for 273 yards and 2 TDs in a Thanksgiving Day game at Detroit. Remarkably, the Lions still won that game 27-14. Simpson’s record lasted a few days short of a year before Walter Payton ran for 275 in a game against the Vikings.