It's always an advantage to be at home in the playoffs, but would anyone be surprised if three of the four home teams lost this week? Houston is a field goal favorite (and might very well lose). New England's 5.5-point spread over Tennessee is largely due to reputation. And Philadelphia is an underdog to Seattle.

The Eagles lost Alshon Jeffery to injury, and it looks like they're not going to have Nelson Agholor for their playoff opener. Agholor hasn't played since Week 13 and didn't make much of an impact when he was on the field, so that's not as big a deal. Greg Ward, Deontay Burnett and Robert Davis should be the main wideouts, and they should be OK in that area, with Ward the No. 1.

But looks like Zach Ertz (rib, kidney) isn't going to be available. He hasn't been cleared for contact, and pretty unlikely he will be by the weekend. Ertz was able to participate in a light walkthrough Wednesday, but that doesn't mean much -- there's no hitting involved in that.

Assuming Ertz doesn't get cleared, Dallas Goedert should be the team's No. 1 tight end, with Joshua Perkins moving into the No. 2, Goedert role. Those would be Carson Wentz's main pass catchers, along with Ward. Not a great situation.

There's also concerning news regarding Miles Sanders (ankle). Initial indications were that he was able to practice on Wednesday, but that was updated; he was listed as DNP. Still a couple of days of practice left, but it no longer looks like he can be counted on to play against Seattle. Philly might need to lead on Boston Scott and Jordan Howard, with Scott (for his pass catching, and excellent play of late) looking like the better bet.

I don't know if a fully healthy Philadelphia team would necessarily beat Seattle, although the Seahawks are also banged-up (especially at running back). But the injuries will make it tougher for them to advance for a likely second-round beating.

--Andy Richardson